Asian Journal of Research and Reports in Neurology

Severe form of Reversible Posterior Encephalopathy Syndrome (PRES) in a Patient with Lupus

Benani Mohamed *

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Hanae El Ghiati

Department of Cardiology, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Chouikh Chakib

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Yassine El Adraoui

Department of Neurology, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Bouayida Ayoub

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Touab Rida

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Mohamed Rabii Andaloussi

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Khalil Mounir

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

Hicham Balkhi

Department of Anesthesia and Critical Care, Faculty of Medicine and Pharmacy, Military Teaching Hospital Mohammed V, Rabat, Morocco.

*Author to whom correspondence should be addressed.

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Abstract

PRES represents a clinico-radiological syndrome indicating spontaneously reversible cerebral distress. It associates predominantly neurological manifestations with white matter signal abnormalities on brain magnetic resonance imaging.

The purpose of our work is to highlight the clinical and evolutionary characteristics of severe forms of PRES, aiming to derive therapeutic and prognostic considerations.

We present a case of a patient with systemic lupus erythematosus complicated by nephropathy, in whom the diagnosis of PRES was established, with a favourable outcome under treatment.

Keywords: Pres, lupus, reversible cerebral distress

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References

Fugate JE, Rabinstein AA. Posterior reversible encephalopathy syndrome: Clinical and radiological manifestations, pathophysiology, and outstanding questions. The Lancet Neurology. 2015; 14(9):914-25.

Legriel S, Pico F, Azoulay E. Understanding posterior reversible encephalopathy syndrome. Annual Update in Intensive Care and Emergency Medicine. 2011:631-53.

Sudulagunta SR, Sodalagunta MB, Kumbhat M, Settikere Nataraju A. Posterior reversible encephalopathy syndrome (PRES). Oxford Medical Case Reports. 2017;4:omx011.

Hugonnet E, Da Ines D, Boby H, Claise B, Petitcolin V, Lannareix V, Garcier JM. Posterior reversible encephalopathy syndrome (PRES): Features on CT and MR imaging. Diagnostic and Interventional Imaging. 2013;94(1):45-52.

Hinduja A. Posterior reversible encephalopathy syndrome: Clinical features and outcome. Frontiers in Neurology. 2020;11:71.

Gao B, Lyu C, Lerner A, McKinney AM. Controversy of posterior reversible encephalopathy syndrome: what have we learnt in the last 20 years? Journal of Neurology, Neurosurgery & Psychiatry. 2018;89(1):14-20.

Kishfy L, Casasola M, Banankhah P, Parvez A, Jan YJ, Shenoy AM, Thomson C, AbdelRazek MA. Posterior reversible encephalopathy syndrome (PRES) as a neurological association in severe COVID-19. Journal of the Neurological Sciences. 2020;414.

Aranas RM, Prabhakaran S, Lee VH. Posterior reversible encephalopathy syndrome associated with hemorrhage. Neurocritical Care. 2009;10:306-12.

Golombeck SK, et al. Fatal atypical reversible posterior leukoencephalopathy syndrome: A case report. Journal of Medical Case Reports. 2013;7(1):14.

Servillo G, et al, Posterior reversible encephalopathy syndrome in intensive care medicine. Intensive Care Medicine. 2007;33(2):230-236.