Acute Lymphocytic Leukaemic and Haemorrhagic Stroke in a 33-year-old Nigerian Man: A Case Report with a Rare Association and Treatment Challenges

Akpekpe Ebiwhiehi John

Neurology Unit, Internal Medicine Department, Federal Medical Centre, Asaba, Delta State, Nigeria.

Ezunu Okechukwu Emmanuel *

Neurology Unit, Internal Medicine Department, Federal Medical Centre, Asaba, Delta State, Nigeria.

Nelson Elisha A

Hematology Unit, Pathology Department, Federal Medical Centre, Asaba, Delta State, Nigeria.

Yakub Yusuf

Neurology Unit, Internal Medicine Department, Federal Medical Centre, Asaba, Delta State, Nigeria.

Okojie Promise Joseph

Radiology Department, Federal Medical Centre, Asaba, Delta State, Nigeria.

Akpekpe Joy

Nursing Department, St. Joseph Hospital Asaba, Delta State, Nigeria.

Ezunu Ngozi Esther

College of Nursing, Onitcha-Uku, Federal Medical Centre, Asaba, Delta State, Nigeria.

Alaba Luke Ayoade

Internal Medicine Department, Federal Medical Centre, Asaba, Delta State, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

Intracerebral hemorrhage can be primary or secondary in origin. The secondary cause includes impairment of the coagulation process. Although acute lymphocytic leukemia (ALL) is a common childhood malignancy, it also occurs in adults. Even less frequently seen is the Chronic Lymphocytic Leukaemia (CLL) as a cause of intracerebral haemorrhage. Older patients with ALL as a cause of Haemorrhagic Stroke have not been reported in our setting. Changes in the classification of ALL have made therapeutic intervention more specific. This leap has not been taken in low-income countries, where patients still struggle with basic investigations. Thus, diagnosis, interventions, and prognosis pose a greater challenge.

We present a 33-year-old carpenter with clinical features, examination, Haematological findings, and serial axial sections of a non-contrast CT scan showing acute left intracerebral haemorrhage in the region of the left basal ganglia and thalamus with intraventricular extension consistent with a rare Association of Acute Lymphocytic leukaemia and Haemorrhagic Stroke in a 33-year-old Nigerian man.

Keywords: Acute lymphocytic leukaemia (ALL), haemorrhagic stroke, treatment challenges, chronic lymphocytic leukaemia


How to Cite

John, Akpekpe Ebiwhiehi, Ezunu Okechukwu Emmanuel, Nelson Elisha A, Yakub Yusuf, Okojie Promise Joseph, Akpekpe Joy, Ezunu Ngozi Esther, and Alaba Luke Ayoade. 2025. “Acute Lymphocytic Leukaemic and Haemorrhagic Stroke in a 33-Year-Old Nigerian Man: A Case Report With a Rare Association and Treatment Challenges”. Asian Journal of Research and Reports in Neurology 8 (1):355-64. https://doi.org/10.9734/ajorrin/2025/v8i1150.

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