Phenobarbitone Toxicity: Management of Acute and Chronic Overdose
Published: 2024-09-01
Page: 107-110
Issue: 2024 - Volume 7 [Issue 1]
Archana Ojha *
Department of Internal Medicine, MLN Medical College, Prayagraj, India.
Gulfam Husain
Department of Internal Medicine, MLN Medical College, Prayagraj, India.
*Author to whom correspondence should be addressed.
Abstract
This is the case study of two patients with phenobarbitone poisoning, one of them was acute phenobarbitone poisoning and the other one was chronic phenobarbitone poisoning. These two cases were managed differently; one with Forced alkaline diuresis and the other one with the Haemodialysis. Phenobarbitone is a long-acting barbiturate which can cause CNS depression, respiratory failure, and hemodynamic instability when consumed in overdose.
Keywords: Phenobarbitone poisoning, CNS inhibition, antiepileptics, anaesthetic agent