Open Access Case Study

Longitudinal Transverse Myelitis with Locked in Syndrome Revealing a Systemic Lupus Erythematosus

Raja Amri, Mohamed Othmen Chouchene, Boutheina Ben Ammou, Manel Loukil, Mohamed Ali Sbai

Asian Journal of Research and Reports in Neurology, Page 1-5

The neuropsychiatric manifestations of lupus are very heterogeneous and are a source of significant morbidity and mortality. Transverse myelitis is a rare but serious complication of systemic lupus erythematosus, classically described as an acute attack with a poor functional prognosis. It most often complicates the course of a previously diagnosed lupus and corresponds clinically to a complete medullary syndrome associating a symmetrical bilateral sensitivo motor deficit and sphincter disorders. We report a rare case of a young woman who was admitted to intensive care for a rapidly evolving flaccid tetraparesis with impaired consciousness. The explorations concluded that there was lupus with an inaugural neurological disorder such as longitudinal transverse myelitis associated with a secondary locked-in syndrome and a pontine ischemic stroke. Our observation has several particularities: the inaugural character and the longitudinal form of lupus myelitis as well as the serious association at the outset with a locked-in syndrome secondary to a cerebrovascular accident.

Open Access Case Study

Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) Associated with Cerebellar Stroke: Case Report and Literature Review

Krishnaprasad Ittilavalappil, Rafat Mohmamed Abdullah Saad, Ginny Varghese

Asian Journal of Research and Reports in Neurology, Page 6-11

11-34 % of acute ischemic stroke patients will develop hyponatremia. Hyponatremia in stroke is usually of the hypoosmolar type caused either due to the Syndrome of Inappropriate Secretion of Anti Diuretic Hormone (SIADH) or Cerebral Salt Wasting Syndrome (CSWS). In Ischemic strokes hyponatremia secondary to SIADH is mostly seen in strokes involving anterior circulation where the hypothalamic-pituitary axis is directly involved. In this report, we present SIADH in a patient with cerebellar stroke and discuss the possible mechanisms of development of SIADH in cerebellar stroke.

Open Access Case Study

Nummular Headache in a Young Nigerian Man-Associated with History of Load Carrying on the Head

Mustapha Adekunle Fatai, Falade Joshua, Nwosu Ifeomachukwu

Asian Journal of Research and Reports in Neurology, Page 12-18

Nummular Headache (NH) is a rare headache disorder characterized by sharply contoured pain fixed in size and shape within a round or elliptical region of the head.

We present  Mr EAO, a 25 year old young man who presented with a history of recurrent well-circumscribed headache of about 7 years duration over a circular area on the vertex of the head measuring, 3.0 cm × 3.0 cm in size, and exhibited a clear-cut boundary from non-painful surrounding.

A brain CT scan showed normal brain and right maxillary sinus polyp with bilateral chronic maxillary sinusitis. An assessment of nummular headache to rule out trigeminal neuralgia was made.

Capsules Tramadol and Neurobion were added to his previous medications of amiptryptilline and Pregabalin and there was a good clinical response.

This patient fulfils most of the International Headache Society diagnostic criteria (ICHD-3 beta) for NH and is currently stable on his medications.

Open Access Case Study

Pachymeningitis in Ulcerative Colitis: Accidental Association?

Abir Derbel, Mariem Ghribi, Olfa Frikha, Leila Mnif, Sameh Marzouk, Nabil Tahri, Zouhir Bahloul

Asian Journal of Research and Reports in Neurology, Page 19-23

Pachymeningitis is a rare disease defined as diffuse or localized inflammatory and fibrosing thickening of the dura mater. Its occurrence in context of Ulcerative colitis has been exceptionally described. We report a case of a woman with ulcerative colitis who developed pachymeningitis in the same time of the flare up of her disease. She was suffered from debilitating headache without any other neurological abnormalities. Brain Magnetic Resonance Imaging was revealed pachymeningitis. The patient presented a recurrent pachymeningitis associated to her ulcerative colitis; Corticosteroids improved initially her digestive and neurological symptoms therefore, a subtotal colectomy and a second round of steroids were indicated with resolution of the symptoms.

Open Access Case Study

Seizures in Pediatrics with COVID-19 Disease: A Case Series of 5 Patients

Borhan Moradveisi, Shirin Behzadi, Avat Karimi, Farima Zakaryaei

Asian Journal of Research and Reports in Neurology, Page 24-28

In December 2019, the outbreak of coronavirus started in China, and after a while, it spread worldwide. These diseases can appear with respiratory and gastrointestinal symptoms in pediatrics, but neurological symptoms like seizures are uncommon. Furthermore, there is no specific data about the nervous system manifestation in children. This case series study is aimed to diagnose COVID-19 in children with nervous system manifestation.