A Case of Listeria Monocytogenes Meningitis in an Elderly Female Complicated by Intracerebral Hemorrhage and Hydrocephalus

Mahpara Nawazish *

Shalamar Institute of Health Sciences Lahore, Pakistan.

Mujeeb ur Rehman Abid Butt

Shalamar Institute of Health Sciences Lahore, Pakistan.

Muhammad Umer Farooq

Shalamar Institute of Health Sciences Lahore, Pakistan.

*Author to whom correspondence should be addressed.


Abstract

An important bacterial pathogen in foodborne illness is Listeria monocytogenes, which affects immunocompromised patients, pregnant females, and people at the extremes of age, including neonates and elderly. The main clinical manifestations of infection in these hosts are central nervous system (CNS) invasion and bacteremia. In contrary to that, normal hosts who ingest high numbers of Listeria may develop self-limited febrile gastroenteritis.

Listeria can lead to unusual and alarming complications such as hydrocephalus and intracerebral hemorrhage (ICH). ICH associated with L. monocytogenes has been observed sporadically.

Listeria is the fifth most common cause of meningitis after H.influenzae, S. pneumoniae, N. meningitides and streptococcus group B, although less common. Meningitis caused by monocytogenes was noted to have highest fatality rate of 22%. Adults with listeria meningitis who do not have serious underlying disease or are not on immunosuppressive drugs have a low mortality rate (0-13%).

A case of listeria meningitis is presented in this paper. An elderly female aged 74 yeras had bacteremia caused by monocytogenes, which got worsened by intracerebral hemorrhage. She presented at first with indefinite symptoms of fever and vomiting for 10 days and ASOC for 2 days and on later admission presented with sudden deterioration of consciousness which prompted further investigations that showed the presence of ICH.

Keywords: Listeria meningitis, intracerebral hemorrhage, hydrocephalus, gram positive rods, elderly patients


How to Cite

Nawazish , Mahpara, Mujeeb ur Rehman Abid Butt, and Muhammad Umer Farooq. 2023. “A Case of Listeria Monocytogenes Meningitis in an Elderly Female Complicated by Intracerebral Hemorrhage and Hydrocephalus”. Asian Journal of Research and Reports in Neurology 6 (1):43-47. https://journalajorrin.com/index.php/AJORRIN/article/view/76.

Downloads

Download data is not yet available.

References

Alammora A, Elamin A. Intracranial Hemorrhage Associated with Listeria monocytogenes Bacteremia in an Elderly Patient on Mycophenolate Mofetil. Cureus; 2022

Magiar O, Vulpie S, Musuroi C, Marincu I, Murariu A, Turaiche M, Musuroi SI, Muntean D, Licker M. Listeria Monocytogenes Meningitis in an Immunocompetent Patient. Infection and Drug Resistance. 2022;989-94.

Pagliano P, Ascione T, Boccia G, De Caro F, Esposito S. Listeria monocytogenes meningitis in the elderly: Epidemiological, clinical and therapeutic findings. Infez Med. 2016;24(2):105-11.

Ooi ST, Lorber B. Gastroenteritis due to Listeria monocytogenes. Clinical infectious diseases. 2005 May 1;40(9):1327-32, Aug 1;14(8).

Gerstein S, Gautam-Goyal P, Goyal S. A case of Listeria monocytogenes meningitis complicated by Hydrocephalus and Intraventricular hemorrhage: A review of treatment options and outcomes. ID Cases. 2020;19:e00704.

Linke K, Rückerl I, Brugger K, Karpiskova R, Walland J, Muri-Klinger S, Tichy A, Wagner M, Stessl B. Reservoirs of Listeria species in three environmental ecosystems. Applied and environmental microbiology. 2014;80(18):5583-92.

Buchanan RL, Gorris LG, Hayman MM, Jackson TC, Whiting RC. A review of Listeria monocytogenes: An update on outbreaks, virulence, dose-response, ecology, and risk assessments. Food Control. 2017;75:1-3.

Brisca G, La Valle A, Campanello C, Pacetti M, Severino M, Losurdo G, Palmieri A, Buffoni I, Renna S. Listeria meningitis complicated by hydrocephalus in an immunocompetent child: Case report and review of the literature. Italian Journal of Pediatrics. 2020;46(1):1-8.

Liang JJ, He XY, Ye H. Rhombencephalitis caused by Listeria monocytogenes with hydrocephalus and intracranial hemorrhage: A case report and review of the literature. World Journal of Clinical Cases. 2019;7(4):538.

Mylonakis E, Hohmann EL, Calderwood SB. Central Nervous System Infection with Listeria monocytogenes: 33 Years' Experience at a General Hospital and Review of 776 Episodes from the Literature. Medicine. 1998;77(5):313- 36.