Possible Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in a Patient with Impaired Consciousness

Shaily Shah *

Department of Medicine, Dhiraj Hospital, SBKS MIRC, Vadodara, Gujarat, India.

Bhaumil Shah

Department of Medicine, Dhiraj Hospital, SBKS MIRC, Vadodara, Gujarat, India.

Pramod Jha

Department of Medicine, Dhiraj Hospital, SBKS MIRC, Vadodara, Gujarat, India.

*Author to whom correspondence should be addressed.


Abstract

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also known as Hashimoto’s encephalopathy (HE) is a rare neurological disorder associated with thyroid autoimmunity. Clinical manifestations include seizures, altered consciousness, transient aphasia, tremors, myoclonus, cognitive impairment, and psychiatric manifestations. Here, we report a case of a 55-year-old female presenting with altered sensorium for 4 days. The patient was a known case of Hypothyroidism, Hypertension and Diabetes. Serologic studies demonstrated elevated levels of anti-thyroid peroxidase (anti-TPO) antibodies. The patient showed a remarkable response to steroid therapy. Hence, the diagnosis of SREAT should be suspected in cases of encephalopathy without an obvious cause, as a good response can be obtained withsteroid therapy; early diagnosis and treatment are very beneficial for such patients.

Keywords: Steroid responsive, Hashimoto’s encephalopathy, anti-TPO antibody, autoimmunity, steroids


How to Cite

Shah, S., Shah, B., & Jha, P. (2023). Possible Steroid-responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) in a Patient with Impaired Consciousness . Asian Journal of Research and Reports in Neurology, 6(1), 23–26. Retrieved from https://journalajorrin.com/index.php/AJORRIN/article/view/72

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