Cerebral Venous Thrombosis: Study of 12 Cases from Southern Brazil

Main Article Content

Otto Jesus Hernandez Fustes
Carlos Arteaga Rodriguez
Georgette Mouchaileh E. Ferreira


Cerebral venous thrombosis (CVT) is a pathology that affects the cerebral venous sinuses causing an ischemic and/or hemorrhagic brain, but, contrary to the arterial cerebral vascular accident, has a clinical presentation with varied signs and symptoms that are difficult to diagnose in the its initial phase. Objective: To present the clinical findings of twelve cases of CVT. Materials and methods: We reviewed the charts of patients admitted with a diagnosis of CVT. Results: We describe 8 females and 4 males, with mean age of 30 years. The most common signs and symptoms were: headache (89%), seizure (55.5%), cranial nerve palsy (44%) and hemiparesis (33%). All patients had diagnoses confirmed by nuclear magnetic resonance of the skull. The risk factors found were the use of oral and puerperium contraceptives. All patients were treated with oral anticoagulant, with no death reported in this series. Conclusion: Venous sinus thrombosis is an uncommon disease that requires a high index of suspected diagnosis by the medical team. The mortality rate is low and the treatment is usually effective.

Thrombosis, cerebral venous sinus, stroke.

Article Details

How to Cite
Fustes, O. J. H., Rodriguez, C. A., & Ferreira, G. M. E. (2021). Cerebral Venous Thrombosis: Study of 12 Cases from Southern Brazil. Asian Journal of Research and Reports in Neurology, 4(1), 11-15. Retrieved from http://journalajorrin.com/index.php/AJORRIN/article/view/30115
Short Communication


Imai WK, Everhart FR, Sanders JM. Cerebral venous sinus thrombosis: Report of a case and review of the literature. Pediatrics. 1982;70(6):965-970.

Al Hashmi K, Al Wahaibi K, Al-Khabori M, Al Lamki S. Characteristics and Outcomes of Patients with Cerebral Venous Sinus Thrombosis. Oman Med J. 2019; 34(5):434-437.
DOI: 10.5001/omj.2019.79

Wasay M, Kaul S, Menon B, Dai AI, Saadatnia M, Malik A, et al. Asian study of cerebral venous thrombosis. J Stroke Cerebrovasc Dis. 2019;28(10):104247.

Saposnik G, Barinagarrementeria F, Brown RD, Bushnell CD, Cucchiara B, Cushman M, deVeber G, Ferro JM, Tsai FY, on behalf of the American Heart Association Stroke Council and the Council on Epidemiology and Prevention. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42:1158–1192.

Ghoneim A, Straiton J, Pollard C, Macdonald K, Jampana R. Imaging of cerebral venous thrombosis. Clin Radiol. 2020;75(4):254-264.
DOI: 10.1016/j.crad.2019.12.009

Villringer A, Mehraein S, Einhäupl KM. Pathophysiological aspects of cerebral sinus venous thrombosis. J Neuroradiol. 1994;21:72-80.

Shahid R, Zafar A, Nazish S, et al. Etiologic and clinical features of cerebral venous sinus thrombosis in Saudi Arabia. J Neurosci Rural Pract. 2019;10(2):278–282.
DOI: 10.4103/jnrp.jnrp_305_18

Dmytriw AA, Song JSA, Yu E, et al. Cerebral venous thrombosis: state of the art diagnosis and management. Neuroradiology. 2018;60:669–685.

Kalita J, Singh VK, Jain N, Misra UK, Kumar S. Cerebral venous sinus thrombosis score and its correlation with clinical and MRI findings. J Stroke Cerebrovasc Dis. 2019;28(11):104324.

Hao Lia, Liqian Cuia, Ziyi Chen, Yue Chen. Risk factors for early-onset seizures in patients with cerebral venous sinus thrombosis: A meta-analysis of observational studies. Seizure: European Journal of Epilepsy. 2019;72:33–39.
Available:https:// doi.org/10.1016/j.seizure.2019.09.006

Einhäupl K, Stam J, Bousser MG, De Bruijn SF, Ferro JM, Martinelli I, Masuhr F. European Federation of Neurological Societies. EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients. Eur J Neurol. 2010;17(10):1229-35.
DOI: 10.1111/j.1468-1331.2010.03011.x.

Ferro JM, Aguiar de Sousa D. Cerebral venous thrombosis: An update. Current Neurology and Neuroscience Reports. 2019; 19: 74.

Guenther G, Arauz A. Cerebral venous thrombosis: A diagnostic and treatment update. Neurología. 2011;26:488-498.

Martínez-Martínez M, Cazorla-García R, Rodríguez de Antonio LA, Martínez-Sánchez P, Fuentes B, Diez-Tejedor E. Hypercoagulability and ischemic stroke in young patients. Neurología. 2010;25:343-348.

Silvis S, De Sousa, D, Ferro J, et al. Cerebral venous thrombosis. Nat Rev Neurol 2017;13:555–565.